Assistant Professor
Biography
Professor Pathak joined Washington University in St. Louis as assistant professor in January 2013 after completing his postdoctoral fellowship in Bioengineering at the University of California-Berkeley.
His research on cell mechanics has been widely published.
Research
Professor Pathak's research interests include biomechanics, biomaterials, cellular mechanics, mechanobiology of the cell, and interactions between cells and extracellular matrices.
He combines experimental and computational techniques to study research problems at the interface of mechanics and biology.
Selected Publications
Pathak, A and S Kumar (2012) Independent regulation of tumor cell migration by matrix stiffness and confinement. Proceedings of the National Academy of Sciences USA (in press) doi:10.1073/pnas.1118073109
Pathak, A and S Kumar (2011) From molecular signal activation to locomotion: an integrated, multiscale analysis of cell motility on defined matrices. PLoS ONE 6(3):e18423.
Pathak, A, RM McMeeking, AG Evans and VS Deshpande, (2010) An analysis of the co-operative mechano-sensitive feedback between intracellular signaling, focal adhesion development and stress fiber contractility. Journal of Applied Mechanics 78(4):041001-12.
Pathak, A, VS Deshpande, RM McMeeking and AG Evans (2008) The simulation of stress fibre and focal adhesion development in cells on patterned substrates. Journal of the Royal Society Interface 5(22):507-524.
Legant, WR, A Pathak, MT Yang, VS Deshpande, RM McMeeking and CS Chen (2009) Microfabricated tissue gauges to measure and manipulate forces from 3D microtissues. Proceedings of the National Academy of Sciences USA 106(25):10097-10102.
Selected Research