Jonathan Silva

314-935-8837
jonsilva@wustl.edu
Whitaker Hall, Room 290G

PhD, Washington University in St. Louis, 2008
MS, Case Western Reserve University, 2004
BS, Johns Hopkins University, 2000

Google Scholar


Affiliations

Jonathan Silva

Biomedical Engineering

Associate Professor

Expertise

Cardiac Arrhythmia, Molecular Imaging, Engineered Cardiomyocytes, Computational Models, Extended Reality

Research

Jonathan R. Silva applies computational and biophysical methods to improve arrhythmia therapies. Current projects include using holograms to guide ablation procedures and creating developing models to guide precision anti-arrhythmic drug prescription based on advanced molecular imaging data.

Biography

Professor Silva joined the Department of Biomedical Engineering at Washington University in St. Louis in July 2012 after receiving the prestigious Burroughs Wellcome Fund Career Award at the Scientific Interface (CASI) as a postdoctoral fellow.

Professor Silva’s laboratory has created novel algorithms that predict whether patients will respond to class I anti-arrhythmic molecules. These predictions are based on machine learning approaches that leverage a deep understanding of drug interaction biophysics. His group also developed software to provide a holographic display to physicians who perform catheter ablations for arrhythmia. This software was recently tested in humans, and the results showed that physician accuracy was significantly improved with the display. A company that he co-founded, SentiAR Inc, is commercializing the technology.

Uses holograms to guide cardiac arrhythmia ablations

In the News

 

 

New model of irregular heartbeat could boost drug efficacy https://engineering.wustl.edu/news/Pages/New-model-of-irregular-heartbeat-could-boost-drug-efficacy.aspxNew model of irregular heartbeat could boost drug efficacy
WUSEF ignites love of research in junior BME student https://engineering.wustl.edu/news/Pages/wusef-ignites-love-of-research-in-junior-bme-student.aspxWUSEF ignites love of research in junior BME student
Edging closer to personalized medicine for patients with irregular heartbeathttps://engineering.wustl.edu/news/Pages/Edging-closer-to-personalized-medicine-for-patients-with-irregular-heartbeat.aspxEdging closer to personalized medicine for patients with irregular heartbeat
Silva named fellow of the American Heart Associationhttps://engineering.wustl.edu/news/Pages/Silva-named-fellow-of-the-American-Heart-Association.aspxSilva named fellow of the American Heart Association