email@example.comWhitaker Hall, Room 290G
Cardiac Arrhythmia, Molecular Imaging, Engineered Cardiomyocytes, Computational Models, Extended Reality
Jonathan R. Silva applies computational and biophysical methods to improve arrhythmia therapies. Current projects include using holograms to guide ablation procedures and creating developing models to guide precision anti-arrhythmic drug prescription based on advanced molecular imaging data.
Professor Silva joined the Department of Biomedical Engineering at Washington University in St. Louis in July 2012 after receiving the prestigious Burroughs Wellcome Fund Career Award at the Scientific Interface (CASI) as a postdoctoral fellow.
Professor Silva’s laboratory has created novel algorithms that predict whether patients will respond to class I anti-arrhythmic molecules. These predictions are based on machine learning approaches that leverage a deep understanding of drug interaction biophysics. His group also developed software to provide a holographic display to physicians who perform catheter ablations for arrhythmia. This software was recently tested in humans, and the results showed that physician accuracy was significantly improved with the display. A company that he co-founded, SentiAR Inc, is commercializing the technology.
Uses holograms to guide cardiac arrhythmia ablations